Fang, Fang; Zheng, Haolin; Li, Weipeng; Mao, Guojiang; Chen, Shanping; Deng, Guo-Jun published the artcile< Metal- and Solvent-Free Synthesis of Maleimide Fused Carbazoles from (Indol-3-yl)cyclohexanones and Maleimides>, Recommanded Product: Methyl 1H-indole-7-carboxylate, the main research area is indolyl cyclohexanone maleimide trimethylsulfoxonium iodide catalyst cyclization; maleimide fused carbazole preparation.
A metal- and solvent-free strategy for the preparation of maleimide-fused carbazoles had been developed. This protocol started from 2-(indol-3-yl)cyclohexanones and maleimides, provided various maleimide-fused carbazoles in 45-90% yields. The present approach was catalyzed by trimethylsulfoxonium iodide and involved a cascade of oxidation, [4+2] annulation, and dehydrogenative aromatization. Moreover, these maleimide-fused carbazole products could be further transformed into other polycyclic aromatic hydrocarbons.
Advanced Synthesis & Catalysis published new progress about Aromatization. 93247-78-0 belongs to class indole-building-block, and the molecular formula is C10H9NO2, Recommanded Product: Methyl 1H-indole-7-carboxylate.
Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles