Synthetic Route of 1069-66-5, Children learn through play, and they learn more than adults might expect. Science experiments are a great way to spark their curiosity, 1069-66-5, Name is Valproic Acid Sodium, SMILES is [O-]C(C(CCC)CCC)=O.[Na+], belongs to indole-building-block compound. In a article, author is Kumar, Amrendra, introduce new discover of the category.
Synthesis of Unprotected and Highly Substituted Indoles by the Ruthenium(II)-Catalyzed Reaction of Phenyl Isocyanates with Diaryl/Diheteroaryl Alkynes/Ethyl-3-phenyl Propiolates
A one-pot transformation has been developed for the synthesis of unprotected and highly substituted indoles by an in situ installed carbamide-directed Ru(II)-catalyzed intermolecular oxidative annulation of phenyl isocyanates with diaryl/diheteroaryl alkynes/ethyl phenyl propiolates in the presence of Cu(OAc)(2)center dot H2O as an oxidant and AgSbF6 as an additive at 120 degrees C within 3 h.
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Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles