Chemistry is the experimental and theoretical study of materials on their properties at both the macroscopic and microscopic levels.In a patent， Product Details of 17826-04-9, Which mentioned a new discovery about 17826-04-9
In this study thirty-three novel indole derivatives were designed and synthesized based on the structure of deformylflustrabromine B (1), a metabolite isolated from the marine bryozoan Flustra foliacea L. The syntheses were carried out using standard methodologies and in good yields. The molecules were tested for their affinities for the alpha4beta2*, alpha3beta 4*, alpha7* and (alpha1)2beta1gammadelta nicotinic acetylcholine receptor (nAChR) subtypes. Binding assays showed that, among these ligands, compound 7c exhibited the highest affinity with K i = 136.1, 93.9 and 862.4 nM for the alpha4beta2*, alpha3beta4*, and alpha7* nAChRs subtypes, respectively. These results indicated that the indole core might be a useful scaffold for the development of new potent and selective nAChR ligands.
Because enzymes can increase reaction rates by enormous factors and tend to be very specific, COA of Formula: C9H6BrNO, typically producing only a single product in quantitative yield, they are the focus of active research.you can also check out more blogs about 17826-04-9
Reference：
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles