In an article, author is Monnappa, Amrutha Balliamada, once mentioned the application of 19005-93-7, Recommanded Product: 19005-93-7, Name is 1H-Indole-2-carbaldehyde, molecular formula is C9H7NO, molecular weight is 145.16, MDL number is MFCD03001425, category is indole-building-block. Now introduce a scientific discovery about this category.
Sodium Dodecyl Sulfate Modified Carbon Nano Tube Paste Electrode for Sensitive Cyclic Voltammetry Determination of Isatin
Purpose: Isatin (IS) is a synthetically significant heterocyclic moiety with an influential pharmacodynamic indole nucleus and hence the electrocatalytic property of has been investigated. Methods: The electrochemical analysis was demonstrated by cyclic voltammetry (CV) in the potential window of 0.2 V to 1.4 V using sodium dodecyl sulfate (SDS) modified carbon nano tube paste electrode (SDSMCNTPE) over a pH range of 6 to 8.5 in 0.2 M phosphate buffer solution (PBS). Surface morphology was studied by using Field emission-scanning electron microscopy (FESEM). Results: The CV study discloses that under ideal condition oxidation of IS arises at a potential of 0.970 V accompanied with an exceptional stability, selectivity and sensitivity for the resultant SDSMCNTPE contrasting to bare carbon nano tube paste electrode (BCNTPE). Individual parameters like electrode surface area, effect of surfactant, detection limit, simultaneous detection of IS and resorcinol (RC) were studied at a scan rate of 0.1 V/s. Scan rate study uncovers the process is diffusion controlled. The oxidation peak current amplified linearly with the surge in concentration of IS under ideal condition. Detection limit (LOD) and limit of quantification (LOQ) in the solution of optimum pH (7.5) at a scan rate of 0.100V/s is 2.4×10(-7) M and 8.2 x 10(-7) M respectively. Conclusion: The proposed electrode portrays excellent repeatability, reproducibility and reliability to resistant electrode fouling.
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Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles