An article Regio- and Stereoselective Synthesis of Enynyl-Aryl Ethers Enabled by Copper/Iodide Tandem Catalysis WOS:000481018100001 published article about C-H BOND; TERMINAL ALKYNES; COPPER; PALLADIUM; HALIDES; ALKENES; ESTERS; IODINATION; COMPLEXES; PHENOLS in [Wu, Yun-Bin; Xiao, Lin; Mao, Chun-Li; Zang, Zhong-Lin; Zhou, Cheng-He; Cai, Gui-Xin] Southwest Univ, Key Lab Luminescent & Real Time Analyt Chem, Minist Educ,Sch Chem & Chem Engn, Key Lab Appl Chem Chongqing Municipal,Inst Bioorg, Chongqing 400715, Peoples R China; [Cai, Gui-Xin] Beijing Natl Lab Mol Sci, Beijing 100190, Peoples R China in 2019, Cited 82. Category: indole-building-block. The Name is 3-(Trifluoromethyl)phenol. Through research, I have a further understanding and discovery of 98-17-9
An approach to preparing enynyl-aryl ethers from phenols and phenylacetylenes is described. This method without extra ligands, overcoming the favored Glaser-Hay dimerization of alkyne, features a wide substrate scope (38 examples including endofolliculina and indole) and the merits of high atom and step economy, good regio- and stereoselectivity (Z-isomers major) in moderate to good isolated yields. Mechanistic studies show that the reaction is enabled by distinctive copper/iodide tandem catalysis.
Category: indole-building-block. About 3-(Trifluoromethyl)phenol, If you have any questions, you can contact Wu, YB; Xiao, L; Mao, CL; Zang, ZL; Zhou, CH; Cai, GX or concate me.
Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles