Authors Kawada, K; Takahashi, I; Arai, M; Sasaki, Y; Asami, T; Yajima, S; Ito, S in AMER CHEMICAL SOC published article about ABSCISIC-ACID; CARLACTONE; STRIGA; 5-DEOXYSTRIGOL; ARABIDOPSIS; REPRESSOR; CAROTENE; RECEPTOR; MAX1 in [Kawada, Kojiro; Arai, Minori; Sasaki, Yasuyuki; Yajima, Shunsuke; Ito, Shinsaku] Tokyo Univ Agr, Dept Biosci, 1-1-1 Sakuragaoka, Tokyo, Tokyo 1568502, Japan; [Takahashi, Ikuo; Asami, Tadao] Univ Tokyo, Dept Appl Biol Chem, Bunkyo Ku, 1-1-1 Yayoi, Tokyo 1138657, Japan; [Asami, Tadao] Japan Sci & Technol Agcy JST, Crest, 4-1-8 Honcho, Kawaguchi, Saitama 3320012, Japan; [Asami, Tadao] King Abdulaziz Univ, Dept Biochem, Jeddah, Saudi Arabia in 2019, Cited 37. Safety of 3-(Trifluoromethyl)phenol. The Name is 3-(Trifluoromethyl)phenol. Through research, I have a further understanding and discovery of 98-17-9
Strigolactones (SLs) are one of the plant hormones that control several important agronomic traits, such as shoot branching, leaf senescence, and stress tolerance. Manipulation of the SL biosynthesis can increase the crop yield. We previously reported that a triazole derivative, TIS108, inhibits SL biosynthesis. In this study, we synthesized a number of novel TIS108 derivatives. Structure-activity relationship studies revealed that 4-(2-phenoxyethoxy)-1-phenyl-2-(1H-1,2,4-triazol-1-yl)butan-1-one (KK5) inhibits the level of 4-deoxyorobanchol in roots more strongly than TIS108. We further found that KK5-treated Arabidopsis showed increased branching phenotype with the upregulated gene expression of AtMAX3 and AtMAX4. These results indicate that KK5 is a specific SL biosynthesis inhibitor in rice and Arabidopsis.
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Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles