Chemistry is an experimental science, Quality Control of: 4-Fluoro-5-hydroxy-2-methylindole, and the best way to enjoy it and learn about it is performing experiments.Introducing a new discovery about 288385-88-6, Name is 4-Fluoro-5-hydroxy-2-methylindole
The invention discloses the treatment of non-small cell lung cancer, renal cancer drug west neeb and intermediate preparation method, the treatment of non-small cell lung cancer, renal cancer drug west neeb of the chemical name is 4 – (4 – fluoro – 2 – methyl indole – 5 – yloxy) – 6 – methoxy – 7 – [3 – (pyrrolidine – 1 – yl) propoxy] quinazoline, structural formula is: ; The process of the invention has simple process, by condensation reaction so that the west neeb intermediate with 5 – hydroxy – 4 – fluoro – 2 – methyl indole synthesis west neeb, improves the atom economy, the selectivity of the reaction and controllability of operation, so that the preparation process of west neeb more controllable, improving the quality of products, promote the economic and technological development of the raw material. (by machine translation)
Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. Quality Control of: 4-Fluoro-5-hydroxy-2-methylindole, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 288385-88-6, in my other articles.
Reference：
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles