Chemistry is the experimental and theoretical study of materials on their properties at both the macroscopic and microscopic levels.In a patent， HPLC of Formula: C9H6BrNO, Which mentioned a new discovery about 17826-04-9
A new synthesis of 5-bromoaplysinopsin (11), 6-bromoaplysinopsin (15) and 3′-demethylaplysinopsin (24) has been developed.A number of their analogues have been synthesized and evaluated for biological activities.Of the compounds tested, compounds 5, 7-9 are active against the fungus Sporotrichum schenckii, 6, 8, and 11 active against Trichophyton mentagrophytes and 8 against Cryptococcus neoformans.Compound 8 also exhibits moderate antiviral activity.Compounds 2, 8 and 9 show significant in vitro activity against Leishmania donovani at a dose of 100 mug/ml.
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Reference：
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles