An article Enantioselective Ammonium Ylide Mediated One-Pot Synthesis of Highly Substituted gamma-Butyrolactones WOS:000540092500012 published article about STEREOSELECTIVE-SYNTHESIS; ASYMMETRIC-SYNTHESIS; CINCHONA ALKALOIDS; DIASTEREOSELECTIVE SYNTHESIS; FACILE SYNTHESIS; 4+1 ANNULATION; EFFICIENT; DERIVATIVES; CYCLOPROPANATION; QUATERNARY in [Oehler, Laura; Djalali, Saveh; Hoefmann, Svenja; Mueller, Clemens; Pietruszka, Joerg; Worgull, Dennis] Heinrich Heine Univ Dusseldorf, Forschungszentrum Julich, Inst Bioorgan Chem, Stetternicher Forst, Bldg 15-8, D-52426 Julich, Germany; [Drennhaus, Till; Pietruszka, Joerg] Forschungszentrum Julich, Inst Bio & Geosci IBG 1, D-52426 Julich, Germany in 2020, Cited 82. Computed Properties of C7H8O. The Name is Benzyl Alcohol. Through research, I have a further understanding and discovery of 100-51-6
An ammonium ylide mediated access towardstrans-beta,gamma-disubstituted,all-trans-alpha,beta,gamma-trisubstituted, and alpha,alpha,beta,gamma-tetrasubstituted gamma-butyrolactones bearing a broad variety of functionalities was developed. Starting from widely accessible benzylidene Meldrum’s acid derivatives and alpha-bromo carbonyl compounds,gamma-butyrolactones were obtained in yields between 32-99% with up to excellent diastereoselectivities (>95:5)viaa DABCO-mediated [2+1] annulation. Utilization of enantiomerically pure cinchona alkaloid derivatives enables the first asymmetric ammonium ylide mediated method to provide (3R, 4R)-beta,gamma-disubstituted and (2R, 3R, 4R)-alpha,beta,gamma-trisubstituted gamma-butyrolactones in moderate to good yields with up to very good enantiomeric ratios (97:3). The scalability of the transformation was proven while determining the absolute configuration.
About Benzyl Alcohol, If you have any questions, you can contact Drennhaus, T; Ohler, L; Djalali, S; Hofmann, S; Muller, C; Pietruszka, J; Worgull, D or concate me.. Computed Properties of C7H8O
Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles