Catalysts are substances that increase the reaction rate of a chemical reaction without being consumed in the process. 77-86-1, Name is 2-Amino-2-(hydroxymethyl)propane-1,3-diol, SMILES is OCC(CO)(N)CO, belongs to indole-building-block compound. In a document, author is Gabrielli, Serena, introduce the new discover, Computed Properties of C4H11NO3.
beta-Nitroacrylates: New Key Precursors of Indole-2-Carboxylates via Fischer Indole Synthesis
Indole 2-carboxylates are very important scaffolds that are widely investigated for their activities and are used as key intermediates of biologically active molecules. Herein, we report a new procedure for the preparation of this class of derivatives, via Fischer indole synthesis, starting from beta-nitroacrylates and arylhydrazines. The protocol permits the production of the title targets in satisfactory overall yields, avoids any wasteful aqueous work-up, and has with evident advantages from a sustainability point of view.
The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 77-86-1 is helpful to your research. Computed Properties of C4H11NO3.
Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles