Cobalt-catalyzed carbonylation of aryl halides was written by Foa, M.;Francalanci, F.;Bencini, E.;Gardano, A.. And the article was included in Journal of Organometallic Chemistry in 1985.Quality Control of 2-Phenylisoindolin-1-one This article mentions the following:
Carbonylation of aromatic and heteroaromatic halides with a catalytic system of alkylcobalt carbonyl complexes, either preformed or made in situ, and bases such as alkoxides, NaOH, and K2CO3 in aliphatic alcs produced aromatic esters, acids, lactones, and lactams in high yield and under mild conditions. New anionic cobalt complexes were formed which were characterized by high reactivity toward aromatic halides. In the experiment, the researchers used many compounds, for example, 2-Phenylisoindolin-1-one (cas: 5388-42-1Quality Control of 2-Phenylisoindolin-1-one).
2-Phenylisoindolin-1-one (cas: 5388-42-1) belongs to indole derivatives. The indole subunit is an almost ubiquitous component of biologically active natural products, and its study has been the focus of research for decades. More than 200 indole derivatives have already been marketed as drugs or are under advanced stages of clinical trials.Quality Control of 2-Phenylisoindolin-1-one
Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles