Reference of Ethyl 3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-thioglucopyranosideOn June 1, 1986, Fugedi, Peter; Garegg, Per J. published an article in Carbohydrate Research. The article was 《A novel promoter for the efficient construction of 1,2-trans linkages in glycoside synthesis, using thioglycosides as glycosyl donors》. The article mentions the following:
Dimethyl(methylthio)sulfonium triflate (I) was used as a promoter for the activation of anomeric thioalkyl (aryl) groups in glycoside synthesis for the construction of 1,2-trans-glycosidic linkages in (1→2), (1→3), (1→4), and (1→6)-linked disaccharides. For example, Me 2,3,4,6-tetra-O-benzoyl-1-thio-β-D-glucopyranoside was treated with 1,2,3,4-tetra-O-benzoyl-β-D-glucopyranose and I in CH2Cl2 in the presence of 4 Å mol. sieve 1 g at 20° to give 92% 1,2,3,4-tetra-O-benzoyl-6-O-(2,3,4,6-tetra-O-benzoyl-β-D-glucopyranosyl)-β-D-glucopyranose. After reading the article, we found that the author used Ethyl 3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-thioglucopyranoside(cas: 99409-32-2Reference of Ethyl 3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-thioglucopyranoside)
Ethyl 3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-thioglucopyranoside(cas: 99409-32-2) belongs to indole.The indole subunit is an almost ubiquitous component of biologically active natural products, and its study has been the focus of research for decades.Reference of Ethyl 3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-thioglucopyranosideThey are capable of binding to a variety of receptors with high affinity and thus have applications in a wide range of therapeutic areas.
Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles