Novel cyclopropapyrroloindole (CPI) bisalkylators bearing methoxycarbonyl and trifluoromethyl groups was written by Fukuda, Yasumichi;Furuta, Hirosuke;Kusama, Yoshie;Ebisu, Hiroyuki;Oomori, Yasuo;Terashima, Shiro. And the article was included in Bioorganic & Medicinal Chemistry Letters in 1998.Recommanded Product: Methyl 5-bromo-1H-indole-2-carboxylate This article mentions the following:
Novel 3-(methoxycarbonyl)-2-(trifluoromethyl)cyclopropapyrroloindole (MCTFCPI) bisalkylators were synthesized, and their antitumor activity was evaluated. Among these derivatives, I was found to exhibit more prominent cytotoxicity and antitumor activity than U-77,779 (bizelesin). In the experiment, the researchers used many compounds, for example, Methyl 5-bromo-1H-indole-2-carboxylate (cas: 210345-56-5Recommanded Product: Methyl 5-bromo-1H-indole-2-carboxylate).
Methyl 5-bromo-1H-indole-2-carboxylate (cas: 210345-56-5) belongs to indole derivatives. In addition to tryptophan, indigo, and indoleacetic acid, numerous compounds obtainable from plant or animal sources contain the indole molecular structure. Moreover, it is known that it controls biofilm formation. However, the role of indole in the cell has not been fully elucidated.Recommanded Product: Methyl 5-bromo-1H-indole-2-carboxylate
Referemce:
Indole alkaloid derivatives as building blocks of natural products from闂佽壈浜崹淇沜illus thuringiensis闂佽壈浜粋鍧闂佽壈浜崹淇沜illus velezensis闂佽壈浜粋鍧 their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles