Synthesis of bis(indole)-1,2,4-triazinones was written by Garg, Neil K.;Stoltz, Brian M.. And the article was included in Tetrahedron Letters in 2005.COA of Formula: C11H9NO3 This article mentions the following:
A facile method for the synthesis of meta- and para-substituted bis(indole)-1,2,4-triazinones, e.g., I, is presented. To access these triazinones, a cyclocondensation reaction between amidrazone and ketoester functionalities was applied. The structures of these interesting compounds were established unambiguously by X-ray crystallog. In the experiment, the researchers used many compounds, for example, Methyl 2-(1H-indol-3-yl)-2-oxoacetate (cas: 18372-22-0COA of Formula: C11H9NO3).
Methyl 2-(1H-indol-3-yl)-2-oxoacetate (cas: 18372-22-0) belongs to indole derivatives. Indole exists overwhelmingly in the 1H-indole form as do other simple indoles. Indole plays a fundamental role for QS in E. coli, being one of the signal molecules responsible for the transcription of a variety of genes (gabT, and tnaB ASTD). COA of Formula: C11H9NO3
Referemce:
Indole alkaloid derivatives as building blocks of natural products from聽Bacillus thuringiensis聽and聽Bacillus velezensis聽and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles