Garg, Neil K. published the artcileThe First Total Synthesis of Dragmacidin D, Formula: C15H14BNO4S, the publication is Journal of the American Chemical Society (2002), 124(44), 13179-13184, database is CAplus and MEDLINE.
The first total synthesis of the biol. significant bis-indole alkaloid dragmacidin D has been achieved. Thermal and electronic modulation provides the key for a series of palladium-catalyzed Suzuki cross-coupling reactions that furnished the core structure of the complex guanidine- and aminoimidazole-containing dragmacidins. Thus, 6-bromo-3-iodo-2-methoxypyrazine was coupled with bromoindole I in the presence of Pd(PPh3)4/MeOH/C6H6/Na2CO3/H2O to give indolopyrazine II. II was then coupled with another indole under similar conditions to give the core silylated bisindole pyrazine III. Following this crucial sequence, a succession of meticulously controlled final events was developed leading to the completion of the natural product.
Journal of the American Chemical Society published new progress about 149108-61-2. 149108-61-2 belongs to indole-building-block, auxiliary class Indole,Boronic acid and ester,Sulfamide,Benzene,Boronic Acids,Boronic Acids,Boronic acid and ester,, name is (1-tosyl-1H-Indol-3-yl)boronic acid, and the molecular formula is C15H14BNO4S, Formula: C15H14BNO4S.
Referemce:
https://www.nature.com/articles/s41429-020-0333-2,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles