An article Iridium-catalyzed Annulation of alpha,beta-Unsaturated Amides with Electron-deficient Conjugated Dienes WOS:000539416400020 published article about C-H FUNCTIONALIZATION; N-METHOXYBENZAMIDES; MULTICOMPONENT SYNTHESIS; OXIDATIVE ANNULATION; BOND ACTIVATION; VINYL ETHERS; BENZAMIDES; HYDROARYLATION; ALKYNES; ALKENES in [Murakami, Kotone; Nishimura, Takahiro] Osaka City Univ, Grad Sch Sci, Dept Chem, Sumiyoshi, Osaka 5588585, Japan; [Nagamoto, Midori] Kyoto Univ, Grad Sch Sci, Dept Chem, Sakyo Ku, Kyoto 6068502, Japan in 2020, Cited 71. The Name is (E)-2-Methylbut-2-enoic acid. Through research, I have a further understanding and discovery of 80-59-1. Application In Synthesis of (E)-2-Methylbut-2-enoic acid
Annulation of alpha,beta-unsaturated amides with electrondeficient 1,3-dienes gave 5,6-dihydropyridin-2(1H)-ones in the presence of a hydroxoiridium catalyst. The reaction proceeded via direct C-H alkylation of acrylamides with conjugated dienes, followed by intramolecular aza-Michael addition, thus giving dihydropyridinones stereoselectively in good yields.
Application In Synthesis of (E)-2-Methylbut-2-enoic acid. Bye, fridends, I hope you can learn more about C5H8O2, If you have any questions, you can browse other blog as well. See you lster.
Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles