Ghorbani-Choghamarani, A; Taherinia, Z in [Ghorbani-Choghamarani, Arash; Taherinia, Zahra] Ilam Univ, Ilam, Iran published Eco-friendly synthesis of 3-aminoimidazo [1, 2-a] pyridines via a one-pot three-component reaction in PEG catalyzed by peptide nanofibers: as hydrogen-bonding organocatalyst in 2020.0, Cited 33.0. Category: indole-building-block. The Name is 3-Hydroxybenzaldehyde. Through research, I have a further understanding and discovery of 100-83-4.
Self-assembled peptide nanofibers have attracted extensive attention; they offer unique templating possibilities, which allow the synthesis of nanostructured materials with high surface areas, and also act as organocatalysts for various transformations in organic chemistry. In the present work, peptide nanofibers as hydrogen-bonding organocatalysts have been developed as efficient organocatalysts for three-component Groebke condensation reactions of aldehydes, isocyanides, and 2-aminopyridines in PEG to afford the corresponding 3-aminoimidazo [1, 2-a] pyridines in high yields without any additives. The key advantages of catalytic systems are (1) using peptide nanofibers as powerful hydrogen-bonding organocatalysts for the synthesis of 3-aminoimidazo [1, 2-a] pyridines, (2) having high catalytic activity, and (3) performing the reactions which can be carried out in PEG, as green solvent instead of the usually used organic solvents. This catalyst could be recycled and reused at least for four times without noteworthy loss of its activity. [GRAPHICS] .
About 3-Hydroxybenzaldehyde, If you have any questions, you can contact Ghorbani-Choghamarani, A; Taherinia, Z or concate me.. Category: indole-building-block
Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles