Gilbert, Eric J.; Ziller, Joseph W.; Van Vranken, David L. published their research in Tetrahedron on December 1 ,1997. The article was titled 《Cyclizations of unsymmetrical bis-1,2-(3-indolyl)ethanes: synthesis of (-)-tjipanazole F1》.Computed Properties of C11H10ClNO2 The article contains the following contents:
The inter- and intramol. dimerization of 3-substituted indoles was studied. The rate and extent of dimerization depends on the indole substituents. The intramol. dimerization of unsym. bis-1,2-(3-indolyl)ethanes could be controlled using either thermodn. reaction conditions (neat trifluoroacetic acid) or kinetic conditions (2 equiv acid/chloroform). This control of regiochem. has been applied to an efficient synthesis of (-)-tjipanazole F1. In addition to this study using Methyl 2-(5-chloro-1H-indol-3-yl)acetate, there are many other studies that have used Methyl 2-(5-chloro-1H-indol-3-yl)acetate(cas: 74339-45-0Computed Properties of C11H10ClNO2) was used in this study.
Methyl 2-(5-chloro-1H-indol-3-yl)acetate(cas: 74339-45-0) is a member of organic chlorides. Organic chlorides are compounds containing a carbon-chlorine bond, which are widely used in the oil field as a wax dissolver. They are generally not present in crude oils and are typically the result of additives, cleaning solutions or chemicals used for oil recovery.Computed Properties of C11H10ClNO2
Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles