Asymmetric amination of 2-substituted indolin-3-ones catalyzed by natural cinchona alkaloids was written by Guo, Jing;Lin, Zi-Hui;Chen, Kai-Bin;Xie, Ying;Chan, Albert S. C.;Weng, Jiang;Lu, Gui. And the article was included in Organic Chemistry Frontiers in 2017.Name: 1-Acetylindolin-3-one This article mentions the following:
The natural quinine-catalyzed enantioselective amination of 2-substituted indolin-3-ones with azodicarboxylates was developed. These reactions provided a broad spectrum of 2,2-disubstituted indolin-3-ones containing a nitrogen-attached quaternary stereocenter at the C2-position in extremely high yields and with excellent enantioselectivities. The readily available catalyst, broad substrate scope, and mild reaction conditions highlighted the practical utility of this process. In the experiment, the researchers used many compounds, for example, 1-Acetylindolin-3-one (cas: 16800-68-3Name: 1-Acetylindolin-3-one).
1-Acetylindolin-3-one (cas: 16800-68-3) belongs to indole derivatives. In addition to tryptophan, indigo, and indoleacetic acid, numerous compounds obtainable from plant or animal sources contain the indole molecular structure. Due to this activity, the indole ring system has become an important component or intermediate in the synthesis of heterocycles.Name: 1-Acetylindolin-3-one
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Indole alkaloid derivatives as building blocks of natural products from聽Bacillus thuringiensis聽and聽Bacillus velezensis聽and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles