Stereoselective Synthesis of Vinylcyclopropa[b]indolines via a Rh-Migration Strategy was written by Guo, Pan;Sun, Wangbin;Liu, Yu;Li, Yong-Xin;Loh, Teck-Peng;Jiang, Yaojia. And the article was included in Organic Letters in 2020.Computed Properties of C7H6N2 This article mentions the following:
A mild rhodium catalytic system has been developed to synthesize vinylcyclopropa[b]indolines through cyclopropanation of indoles with vinyl carbenoids generated from ring opening of cyclopropenes in situ. By employing a Rh-migration strategy, the products can be obtained with good to excellent E:Z ratios (≤99:1) and complete diastereoselectivity (≤99:1). This method is easy, has a low catalyst loading, and works for a broad range of functionalities. In the experiment, the researchers used many compounds, for example, 1H-Pyrrolo[2,3-b]pyridine (cas: 271-63-6Computed Properties of C7H6N2).
1H-Pyrrolo[2,3-b]pyridine (cas: 271-63-6) belongs to indole derivatives. Indole is an important structural motif of various drugs, therapeutic leads besides its prevalence in numerous natural products, agrochemicals, perfumery, and dyes. Moreover, it is known that it controls biofilm formation. However, the role of indole in the cell has not been fully elucidated.Computed Properties of C7H6N2
Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles