On May 8, 2001, Gwaltney, Stephen L., II; Jae, Hwan-Soo; Kalvin, Douglas M.; Liu, Gang; Sham, Hing L.; Li, Qun; Claiborne, Akiyo K.; Wang, Le; Barr, Kenneth J.; Woods, Keith W. published a patent.HPLC of Formula: 256935-86-1 The title of the patent was Preparation of oxazoline antiproliferative agents. And the patent contained the following:
R2ZR [I; R = alkyl-, alkoxy, or alkylthio-trisubstituted Ph; R2 = (un)substituted cycloalk(en)yl, -heterocyclyl, -aryl, etc.; Z = (4-alkyl)-2-oxazoline-2,5-diyl or 4,4-dialkyl-2-oxazoline-2,5-diyl] were prepared Thus, 3,4,5-trimethoxybenzaldehyde was condensed with MeNO2 and the reduced product amidated by 4-(Me2N)C6H4COCl to give, after cyclization, I [R = C6H2(OMe)3-3,4,5, R2 = C6H4(NMe2)-4, Z = 2-oxazoline-2,5-diyl]. Data for biol. activity of I were given. The experimental process involved the reaction of 6-Chloro-1H-indole-5-carboxylic acid(cas: 256935-86-1).HPLC of Formula: 256935-86-1
The Article related to oxazoline preparation antiproliferative agent, antitumor agent oxazoline preparation, Heterocyclic Compounds (More Than One Hetero Atom): Oxazoles, Isoxazoles and other aspects.HPLC of Formula: 256935-86-1
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Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles