Modular synthesis of 4-aminocarbonyl substituted 1,8-naphthalimides and application in single molecule fluorescence detection was written by Hearn, K. N.;Nalder, T. D.;Cox, R. P.;Maynard, H. D.;Bell, T. D. M.;Pfeffer, F. M.;Ashton, T. D.. And the article was included in Chemical Communications (Cambridge, United Kingdom) in 2017.SDS of cas: 480-91-1 This article mentions the following:
Robust methodol. to install amide, carbamate, urea and sulfonamide functionality to the 1,8-naphthalimide scaffold has been developed and exemplified. New benzamidonaphthalimide 6, synthesized using this approach, was found to be sensitive to base whereupon fluorescence emission strongly increases (>10-fold) and red-shifts (>4000 cm-1). The optical properties of deprotonated 6 allow for single mol. fluorescence detection, the first example of such behavior from this class of fluorophore. In the experiment, the researchers used many compounds, for example, Isoindolin-1-one (cas: 480-91-1SDS of cas: 480-91-1).
Isoindolin-1-one (cas: 480-91-1) belongs to indole derivatives. Indole could be stereoselectively alkylated with chiral cyclopentyl sulfone reagent. Indole plays a fundamental role for QS in E. coli, being one of the signal molecules responsible for the transcription of a variety of genes (gabT, and tnaB ASTD). SDS of cas: 480-91-1
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Indole alkaloid derivatives as building blocks of natural products from聽Bacillus thuringiensis聽and聽Bacillus velezensis聽and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles