Visible-light-induced intramolecular charge transfer in the radical spirocyclization of indole-tethered ynones was written by Ho, Hon Eong;Pagano, Angela;Rossi-Ashton, James A.;Donald, James R.;Epton, Ryan G.;Churchill, Jonathan C.;James, Michael J.;O’Brien, Peter;Taylor, Richard J. K.;Unsworth, William P.. And the article was included in Chemical Science in 2020.Recommanded Product: 2-(2-Phenyl-1H-indol-3-yl)acetic acid This article mentions the following:
Indole-tethered ynones form an intramol. electron donor-acceptor complex that can undergo visible-light-induced charge transfer to promote thiyl radical generation from thiols. This initiates a novel radical chain sequence, based on dearomatizing spirocyclization with concomitant C-S bond formation. Sulfur-containing spirocycles are formed in high yields using this simple and mild synthetic protocol, in which neither transition metal catalysts nor photocatalysts are required. The proposed mechanism is supported by various mechanistic studies, and the unusual radical initiation mode represents only the second report of the use of an intramol. electron donor-acceptor complex in synthesis. In the experiment, the researchers used many compounds, for example, 2-(2-Phenyl-1H-indol-3-yl)acetic acid (cas: 4662-03-7Recommanded Product: 2-(2-Phenyl-1H-indol-3-yl)acetic acid).
2-(2-Phenyl-1H-indol-3-yl)acetic acid (cas: 4662-03-7) belongs to indole derivatives. In addition to tryptophan, indigo, and indoleacetic acid, numerous compounds obtainable from plant or animal sources contain the indole molecular structure.Indole was synthesized in moderate yield via an o-naphthoquinone catalyzed tandem cross-coupling of substituted aniline and benzylamine under aerobic oxidation conditions.Recommanded Product: 2-(2-Phenyl-1H-indol-3-yl)acetic acid
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Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles