Aly, AA; Ibrahim, MAA; El-Sheref, EM; Hassan, AMA; Brow, AB in [Aly, Ashraf A.; Ibrahim, Mahmoud A. A.; El-Sheref, Essmat M.; Hassan, Alaa M. A.] Menia Univ, Fac Sci, Chem Dept, El Minia 61519, Egypt; [Brow, Alan B.] Florida Inst Technol, Chem Dept, Melbourne, FL 32901 USA published Prospective new amidinothiazoles as leukotriene B4 inhibitors in 2019.0, Cited 50.0. Quality Control of 4′-Hydroxyacetophenone. The Name is 4′-Hydroxyacetophenone. Through research, I have a further understanding and discovery of 99-93-4.
An efficient and one-step synthesis of the versatile, hitherto new derivatives resembling LY293111, a prospective potent antagonist of the leukotriene B4 (LTB4) receptor, were reported. The strategy was based on the synthesis of an amidinothiazole ring, connected with phenoxy group. The synthesized compounds were structurally confirmed by IR, NMR (including 2D-NMR), mass spectra and elemental analyses as well. The binding sites of LTB4 receptors -namely BLT1 and BLT2 were identified. Docking results suggested that some amidinobisthiazol-4-ones have potent activities towards BLT1 and BLT2 receptors. (C) 2018 Elsevier B.V. All rights reserved.
Quality Control of 4′-Hydroxyacetophenone. Bye, fridends, I hope you can learn more about C8H8O2, If you have any questions, you can browse other blog as well. See you lster.
Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles