Hrizi, Asma; Cailler, Manon; Romdhani-Younes, Moufida; Carcenac, Yvan; Thibonnet, Jerome published the artcile< Synthesis of New Highly Functionalized 1H-Indole-2-carbonitriles via Cross-Coupling Reactions>, Reference of 399-76-8, the main research area is alkenyl indole carbonitrile preparation; aryl indole carbonirile preparation; 1H-indole-2-carbonitriles; Heck; Sonogashira; Stille; Suzuki–Miyaura.
An approach for the preparation of polysubstituted indole-2-carbonitriles through a cross-coupling reaction of compounds 1-(but-2-ynyl)-1H-indole-2-carbonitriles and 1-benzyl-3-iodo-1H-indole-2-carbonitriles was described. The reactivity of indole derivatives with iodine at position 3 was studied using cross-coupling reactions. The Sonogashira, Suzuki-Miyaura, Stille and Heck cross-couplings afforded a variety of di-, tri- and tetra-substituted indole-2-carbonitriles.
Molecules published new progress about Alkenes Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 399-76-8 belongs to class indole-building-block, and the molecular formula is C9H6FNO2, Reference of 399-76-8.
Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles