Consecutive C1-Homologation / Displacement Strategy for Converting Thiosulfonates into O,S-Oxothioacetals was written by Ielo, Laura;Pillari, Veronica;Miele, Margherita;Holzer, Wolfgang;Pace, Vittorio. And the article was included in Advanced Synthesis & Catalysis in 2020.HPLC of Formula: 14204-27-4 This article mentions the following:
A conceptually intuitive synthesis of oxothioacetals RSCH2OR1 [R = Me, Ph, 4-FC6H4, 2-F3CC6H4, (4,6-dimethylpyrimidin-2-yl); R1 = Me, 2-BrC6H4, 1-naphthyl, etc.] was reported starting from thiosulfonates as electrophilic sulfur donors. The installation of a reactive CH2Cl motif with a homologating carbenoid reagent, followed by the immediate nucleophilic displacement with alc. groups [(hetero)-aromatic, aliphatic] offered a convenient access to the title compounds RSCH2OR1. Genuine chemoselectivity was uniformly observed in the case of multi-functionalized systems. In the experiment, the researchers used many compounds, for example, 2-(Phenylthio)isoindoline-1,3-dione (cas: 14204-27-4HPLC of Formula: 14204-27-4).
2-(Phenylthio)isoindoline-1,3-dione (cas: 14204-27-4) belongs to indole derivatives. In addition to tryptophan, indigo, and indoleacetic acid, numerous compounds obtainable from plant or animal sources contain the indole molecular structure. Moreover, it is known that it controls biofilm formation. However, the role of indole in the cell has not been fully elucidated.HPLC of Formula: 14204-27-4
Referemce:
Indole alkaloid derivatives as building blocks of natural products from聽Bacillus thuringiensis聽and聽Bacillus velezensis聽and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles