Chemistry, like all the natural sciences, Recommanded Product: 320-67-2, begins with the direct observation of nature— in this case, of matter.320-67-2, Name is 5-Azacytidine, SMILES is OC[C@@H]1[C@H]([C@H]([C@H](N2C(N=C(N=C2)N)=O)O1)O)O, belongs to indole-building-block compound. In a document, author is Aksenov, Alexander, V, introduce the new discover.
A highly efficient one-pot procedure combining conjugate addition of Grignard reagents to (2-nitroalkenyl)indoles and sub-sequent Bronsted acid-assisted spirocyclization allowed for preparation of 4 ‘ H-spiro[indole-3,5 ‘-isoxazoles] in a diastereomerically selective fashion. Utilization of alkyl Grignard reagents provided an easy access to 4 ‘-alkylsubstituted derivatives hardly available by other means.
Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions. you can also check out more blogs about 320-67-2. Recommanded Product: 320-67-2.
Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles