In an article, author is Ieronimo, Gabriella, once mentioned the application of 10309-37-2, Product Details of 10309-37-2, Name is Bakuchiol, molecular formula is C18H24O, molecular weight is 256.3826, MDL number is MFCD01707441, category is indole-building-block. Now introduce a scientific discovery about this category.
A novel synthesis of N-hydroxy-3-aroylindoles and 3-aroylindoles
A straightforward indole synthesis via annulation of C-nitrosoaromatics with conjugated terminal alkynones was realised achieving a simple, highly regioselective, atom- and step economical access to 3-aroylindoles in moderate to good yields. Further functionalizations of indole scaffolds were investigated and an easy way to JWH-018, a synthetic cannabinoid, was achieved.
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Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles