On March 3, 2017, Jiang, Xue; Tang, Weijun; Xue, Dong; Xiao, Jianliang; Wang, Chao published an article.Synthetic Route of 52537-00-5 The title of the article was Divergent Dehydrogenative Coupling of Indolines with Alcohols. And the article contained the following:
The dehydrogenative coupling of indolines with alcs. catalyzed by an iridium complex has been achieved to afford both N- and C3-alkylated indoles selectively, by simply changing the addition time of a base additive. The iridacycle catalyst plays multiple roles in these reactions, which dehydrogenates both amines and alcs. and catalyzes the coupling reactions. Mechanistic studies reveal that a borrowing hydrogen-dehydrogenation process and a dehydrogenation-borrowing hydrogen process are involved in N-alkylation and C3-alkylation reactions, resp. The C3-alkylation reaction involves the direct coupling of two sp3 carbon centers. The experimental process involved the reaction of 6-Chloro-2,3-dihydro-1H-indole(cas: 52537-00-5).Synthetic Route of 52537-00-5
The Article related to iridium catalyst dehydrogenative coupling indoline alc, indole alkylated preparation, Heterocyclic Compounds (One Hetero Atom): Indoles, Indolizines, Carbazoles, and Other Arenopyrroles and other aspects.Synthetic Route of 52537-00-5
Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles