Jiang, Xue; Wang, Chao; Wei, Yawen; Xue, Dong; Liu, Zhaotie; Xiao, Jianliang published an article in 2014, the title of the article was A General Method for N-Methylation of Amines and Nitro Compounds with Dimethylsulfoxide.SDS of cas: 52537-00-5 And the article contains the following content:
DMSO reacts with a broad range of amines in the presence of formic acid, providing a novel, green and practical method for amine methylation. The protocol also allows the one-pot transformation of aromatic nitro compounds into di-Me amines in the presence of a simple iron catalyst. A mechanistic study indicated that the synthesis of the target compounds was achieved by a methylene group transfer from DMSO to an amine, formation of an imine intermediate and subsequent reduction of this imine by formic acid. A reaction of 2-[2-(1,3-benzodioxolyl)ethyl]-1,2,3,4-tetrahydroquinoline with DMSO/HCO2H gave 2-[2-(1,3-benzodioxolyl)ethyl]-1,2,3,4-tetrahydro-1-(methyl)quinoline (allocuspareine, galipinine). The experimental process involved the reaction of 6-Chloro-2,3-dihydro-1H-indole(cas: 52537-00-5).SDS of cas: 52537-00-5
The Article related to methylation alkylation amine dmso, secondary primary amine nitrobenzene methylation dmso formic acid, dmso, amines, deuterium labelling, formic acid, methylation, Alkaloids: Alkaloids Containing One Nitrogen Atom In A Ring and other aspects.SDS of cas: 52537-00-5
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Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles