Kan, Chun; Shao, Xiaotao; Song, Fan; Xu, Jinbao; Zhu, Jing; Du, Lei published the artcile< Bioimaging of fluorescence rhodamine-based probe for reversible detection of Hg(II) and its application in real water environment>, COA of Formula: C30H36N4O2, the main research area is rhodamine mercury lake water fluorescence quenching biol imaging.
Mercury is a typical serious pollutant certified by relevant authorities, it is harmful not only to biol. health but also to the ecol. environment and its superior detection approach remains challenging. About this research, a novel reversible fluorescent probe (RBST) based on 2-thiopheneacetyl chloride and Rhodamine B was designed, synthesized and established to develop as a chemosensor. Its sensing behavior, especially for various common metal ions, was detected by UV-visible spectrum and fluorescence spectrum. RBST displayed a satisfactory sensitivity and selectivity fluorescent response towards Hg2+ in a solution of EtOH/H2O (2,1, volume/volume), giving a higher combining constant of 3.03 × 104 M-1 and a lower detection limit of 0.11μM resp. Fluorescence quenched presented a reversible behavior with a certain amount of S2- was added under the condition of containing Hg2+. Besides, the practicality of the probe in sensing Hg2+ in real water samples was further proved. Results of this study suggested that the fluorescent reversible probe excels in biol. applications and can be applied in MCF-7 cells, zebrafish and soybean rhizome tissues to detect Hg2+.
Microchemical Journal published new progress about Biological imaging. 950846-89-6 belongs to class indole-building-block, and the molecular formula is C30H36N4O2, COA of Formula: C30H36N4O2.
Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles