Indole, first isolated in 1866, has the molecular formula C8H7N, and it is commonly synthesized from phenylhydrazine and pyruvic acid, 19005-93-7, formula is C9H7NO, Name is 1H-Indole-2-carbaldehyde. although several other procedures have been discovered.Indole is a colourless solid having a pleasant fragrance in highly dilute solutions. It melts at 52.5° C (126.5° F). Electric Literature of 19005-93-7.
Kanta Mahato, Rajani;Kumar Mudi, Prafullya;Deb, Mayukh;Biswas, Bhaskar research published 《 A Direct metal-free synthetic approach for the efficient production of privileged benzimidazoles in water medium under aerobic condition》, the research content is summarized as follows. A metal-free methodol. for the synthesis of 1,2-disubstituted and 2-substituted benzimidazoles with high to excellent yields was developed. The course of synthesis involved easy work-up, straightforward purification, inexpensive reaction setup and wide substrate scope under extremely mild and operationally simple conditions which makes the synthetic strategy more lucrative, practical and reliable. The serious challenge to carry out these reactions in a pure aqueous medium was achieved at 75°C in presence of air bubbles. The applicability of this operationally simple and metal-free synthetic approach for the gram-scale synthesis of benzimidazole derivatives with good yield (∼74%) further strengthens its potentiality for the synthesis at an industrial scale.
Electric Literature of 19005-93-7, 1H-Indole-2-carbaldehyde is a useful research compound. Its molecular formula is C9H7NO and its molecular weight is 145.16 g/mol. The purity is usually 95%.
1H-Indole-2-carbaldehyde is a useful research chemical used as a reactant in the synthesis of substituted 2-amino-4H-chromenes and benzochromenes using K2CO3 as catalyst.
1H-Indole-2-carbaldehyde is a solvent that has been used in the protein data and molecular modeling study. The 1H NMR spectrum of this compound showed an intense signal at δ 4.8 ppm, corresponding to the hydroxyl proton. This solvent also has fluorescence properties, as shown by its photophysical and structural analysis. The 1H-indole-2-carbaldehyde molecule has an active methylene group and an oxindole ring with amine substituents., 19005-93-7.
Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles