On August 31, 1977, Kitamura, Reiko; Fujii, Harue; Hashiba, Kazuhiko; Somei, Masanori; Kaneko, Chikara published an article.Related Products of 65417-22-3 The title of the article was Studies on the N-oxides of π-deficient N-heteroaromatics. Part XXVII. Ring-contraction reactions of methyl benz[d]-3,1-oxazepine 5-carboxylates. And the article contained the following:
Irradiation of the quinoline oxide I (R = Ph, R1 = H) in Me2CO for 5 h gave 82% Me 2-phenylindole-3-carboxylate (II; R = Ph) and 9% Me 2-phenylquinoline-4-carboxylate. If the irradiation was terminated after 20 mins, ∼80% oxazepine III (R = Ph, R1 = H) was obtained, which on further irradiation, or on refluxing in MeOH in the dark (10 h) gave II (R = Ph). Similar irradiation of I (R = Me, R1 = H) in Me2CO or MeCN gave the phenylindole II (R = Me). Irradiation of I (R = Ph, R1 = Me) gave the oxazepine III (R = Ph, R1 = Me) which on heating in MeOH in a sealed tube for 2 h at 100° gave 21% II (R = Ph) and 23% 3H-indole IV (R = Ph, R1 = Me), the latter being converted into II (R = Ph) by heating in MeOH (100° in a sealed tube, 4 h) or in MeOH at room temperature in presence of HCl or KOH. Therefore the Me quinolinecarboxylates I were converted into the Me indolecarboxylates II via the oxazepines III and the 3H-indoles IV. The experimental process involved the reaction of Methyl 2-methyl-1H-indole-3-carboxylate(cas: 65417-22-3).Related Products of 65417-22-3
The Article related to quinolinecarboxylate oxide photolysis, benzoxazepinecarboxylate ring contraction, indolecarboxylate, Heterocyclic Compounds (One Hetero Atom): Quinolines and Isoquinolines and other aspects.Related Products of 65417-22-3
Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles