Synthesis of substituted isatins was written by Klein, Larry L.;Tufano, Michael D.. And the article was included in Tetrahedron Letters in 2013.Reference of 150560-58-0 This article mentions the following:
Isatins are valuable intermediates for heterocyclic chem. Most of the common methods for their production are less than adequate when the number and lipophilicity of substituents on the targeted isatin are increased. An an alternative method for preparation of isatins, e.g., I, were developed. In the experiment, the researchers used many compounds, for example, 5-Isopropylindoline-2,3-dione (cas: 150560-58-0Reference of 150560-58-0).
5-Isopropylindoline-2,3-dione (cas: 150560-58-0) belongs to indole derivatives. Indole, also called Benzopyrrole, a heterocyclic organic compound occurring in some flower oils, such as jasmine and orange blossom, in coal tar, and in fecal matter. Moreover, it is known that it controls biofilm formation. However, the role of indole in the cell has not been fully elucidated.Reference of 150560-58-0
Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles