Chirality detection by Raman spectroscopy: The case of enantioselective interactions between amino acids and polymer-modified chiral silica was written by Kong, Huanjun;Sun, Xueping;Yang, Liu;Liu, Xinling;Yang, Haifeng;Jin, Ren-Hua. And the article was included in Analytical Chemistry (Washington, DC, United States) in 2020.HPLC of Formula: 153-94-6 This article mentions the following:
In chirality research area, it is of interest to reveal the chiral feature of inorganic nanomaterials and their enantioselective interactions with biomols. Although common Raman spectroscopy is not regarded as a direct chirality anal. tool, it is in fact effective and sensitive to study the enantioselectivity phenomena, which is demonstrated by the enantio-discrimination of amino acid enantiomers using the polydopamine-modified intrinsically chiral SiO2 nanofibers in this work. The Raman scattering intensities of an enantiomer of cysteine are more than twice as high as those of the other enantiomer with opposite handedness. Similar results were also found in the cases of cystine, phenylalanine, and tryptophan enantiomers. In turn, these organic mols. could be used as chirality indicators for SiO2, which was clarified by the unique Raman spectra-derived mirror-image relationships. Thus, an indirect chirality detection method for inorganic nanomaterials was developed. In the experiment, the researchers used many compounds, for example, H-D-Trp-OH (cas: 153-94-6HPLC of Formula: 153-94-6).
H-D-Trp-OH (cas: 153-94-6) belongs to indole derivatives. Indole could be stereoselectively alkylated with chiral cyclopentyl sulfone reagent. Indole was synthesized in moderate yield via an o-naphthoquinone catalyzed tandem cross-coupling of substituted aniline and benzylamine under aerobic oxidation conditions.HPLC of Formula: 153-94-6
Referemce:
Indole alkaloid derivatives as building blocks of natural products from聽Bacillus thuringiensis聽and聽Bacillus velezensis聽and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles