Reaction of indoles with trifluoroacetic acid was written by Kost, A. N.;Budylin, V. A.;Romanova, N. N.;Matveeva, E. D.. And the article was included in Khimiya Geterotsiklicheskikh Soedinenii in 1981.Related Products of 16732-64-2 This article mentions the following:
Trifluoroacetylindoles I (R = H, 4-Me, 6-Br, 7-Ph) are obtained in 10, 27, 12, and 3% yields, resp., when the corresponding indole-2-carboxylic acids are heated with F3CCO2H 13-26 h on a boiling water bath. In the experiment, the researchers used many compounds, for example, 4-Bromo-1H-indole-2-carboxylic acid (cas: 16732-64-2Related Products of 16732-64-2).
4-Bromo-1H-indole-2-carboxylic acid (cas: 16732-64-2) belongs to indole derivatives. The indole subunit is an almost ubiquitous component of biologically active natural products, and its study has been the focus of research for decades. Indole plays a fundamental role for QS in E. coli, being one of the signal molecules responsible for the transcription of a variety of genes (gabT, and tnaB ASTD). Related Products of 16732-64-2
Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles