On December 6, 2012, Lagrange, Alain; Mignon, Marie published a patent.Application In Synthesis of 6-Chloro-2,3-dihydro-1H-indole The title of the patent was Hair dye composition comprising a (hydroxy)indoline coupler in a medium rich in fatty substances. And the patent contained the following:
The present invention relates to a composition for dyeing keratin fibers, such as hair, comprising: a fatty substance, a surfactant; an oxidation base, one or more indoline couplers (I, R1 = e.g., H, C1-10 alkyl, C2-10 alkenyl; R2 = OH, halo, C1-10 alkyl, C3-10 alkenyl; R2 being connected to a heterocycle via a C-C bond, a carboxyl or alkoxycarbonyl and n = 0-4; R3 = halo, C1-10 alkyl, C3-10 alkenyl, OH, C1-8 alkylthio, amino, and p = 0-3, and also salts, optical and geometrical isomers and tautomers, and hydrates thereof), and a basifying agent;and the fatty substance content at 25% by weight The present invention also relates to a process of using this composition in the presence of a chem. oxidizing agent, and to multicompartment devices suitable for the implementation of the invention. Thus, a formulation contained 2,3-diaminodihydropyrazolopyrazolone dimethosulfonate (oxidation base) 2×10-2 and 1-methylindolin-4-ol (coupler) 2×10-2 mol in addition to other cosmetic ingredients. The experimental process involved the reaction of 6-Chloro-2,3-dihydro-1H-indole(cas: 52537-00-5).Application In Synthesis of 6-Chloro-2,3-dihydro-1H-indole
The Article related to hair dye hydroxyindoline coupler fatty substance, Essential Oils and Cosmetics: Hair Preparations and other aspects.Application In Synthesis of 6-Chloro-2,3-dihydro-1H-indole
Referemce:
Indole alkaloid derivatives as building blocks of natural products from聽Bacillus thuringiensis聽and聽Bacillus velezensis聽and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles