Lai, Yi-Huan; Wu, Run-Shi; Huang, Jie; Huang, Jun-Yu; Xu, Da-Zhen published the artcile< Iron-Catalyzed Oxidative Coupling of Indoline-2-ones with Aminobenzamides via Dual C-H Functionalization>, Quality Control of 20870-77-3, the main research area is oxindole aminobenzamide iron catalyst oxidative coupling reaction; spioroindolinequinazoline dione preparation.
We describe an unprecedented dual C-H functionalization of indolin-2-one via an oxidative C(sp3)-H/N-H/X-H (X = N, C, S) cross-coupling protocol, which was catalyzed by a simple iron salt under mild and ligand-free conditions and employs air (mol. oxygen) as the terminal oxidant. This method was readily applicable for the construction of tetrasubstituted carbon centers from methylenes and provides a wide variety of spiro N-heterocyclic oxindoles.
Organic Letters published new progress about Amino amides Role: RCT (Reactant), RACT (Reactant or Reagent). 20870-77-3 belongs to class indole-building-block, and the molecular formula is C8H6ClNO, Quality Control of 20870-77-3.
Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles