Light microscopic autoradiography of rat retinae after intravitreal injection of [3H]6-methoxy-tetrahydro]β-carboline was written by Leino, Markku;Markkanen, Seppo;Airaksinen, Mauno M.;Gynther, Jukka;Kari, Ilkka. And the article was included in Acta Ophthalmologica in 1984.Application of 20315-68-8 This article mentions the following:
The autoradiog. retinal distribution of intravitreally injected [3H]6-methoxy-tetrahydro-β-carboline (6-MeO-THBC) in rats was studied. The synaptic and ganglion cell layers accumulate pronounced radioactivity, as do some intra- and extracellular locations in the inner nuclear layer and the outer segments of the photoreceptors. The pigment epithelium gradually accumulates a very dense band of radioactivity. The relation between 6-MeO-THBC, melatonin and other 5-methoxy-indoles is discussed. In the experiment, the researchers used many compounds, for example, 6-Methoxy-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole (cas: 20315-68-8Application of 20315-68-8).
6-Methoxy-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole (cas: 20315-68-8) belongs to indole derivatives. Indole is an important structural motif of various drugs, therapeutic leads besides its prevalence in numerous natural products, agrochemicals, perfumery, and dyes.Indole was synthesized in moderate yield via an o-naphthoquinone catalyzed tandem cross-coupling of substituted aniline and benzylamine under aerobic oxidation conditions.Application of 20315-68-8
Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles