Li, Long; Zhou, Bo; Wang, Yong-Heng; Shu, Chao; Pan, Yi-Fei; Lu, Xin; Ye, Long-Wu published an article in 2015, the title of the article was Zinc-Catalyzed Alkyne Oxidation/C-H Functionalization: Highly Site-Selective Synthesis of Versatile Isoquinolones and β-Carbolines.Recommanded Product: 1,5-Dimethyl-1H-indole-2-carbaldehyde And the article contains the following content:
An efficient zinc(II)-catalyzed alkyne oxidation/C-H functionalization sequence was developed, leading to a highly site-selective synthesis of a variety of isoquinolones, e.g., I, and β-carbolines, e.g., II. Importantly, in contrast to the well-established gold-catalyzed intermol. alkyne oxidation, over-oxidation was completely suppressed in this system and the reaction most likely proceeds by a Friedel-Crafts-type pathway. Mechanistic studies and theor. calculations were described. The experimental process involved the reaction of 1,5-Dimethyl-1H-indole-2-carbaldehyde(cas: 883526-76-9).Recommanded Product: 1,5-Dimethyl-1H-indole-2-carbaldehyde
The Article related to ynamide benzyl alkyne oxidation regioselective functionalization zinc triflate, indolylmethyl ynamide alkyne oxidation regioselective functionalization zinc triflate, isoquinolone preparation, carboline beta preparation, heterocycles, homogeneous catalysis, nitrogen oxides, synthetic methods, zinc and other aspects.Recommanded Product: 1,5-Dimethyl-1H-indole-2-carbaldehyde
Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles