On December 8, 2010, Lin, Ning; Chen, Miao-Miao; Luo, Ren-Shi; Deng, Yan-Qiu; Lu, Gui published an article.Safety of H-Idc-OH The title of the article was Indolinylmethanol catalyzed enantioselective Reformatsky reaction with ketones. And the article contained the following:
A series of chiral indolinylmethanol ligands have been applied for the first time in the asym. Reformatsky reaction of an α-bromoester with ketones. In the presence of NiBr2 and zinc powder, up to 75% yield and 87% ee were obtained for a variety of aromatic and aliphatic ketones. The use of Ni(acac)2 resulted in 96% ee although the corresponding yield was low. This process provided a convenient method to access synthetically useful chiral β-hydroxyesters. The experimental process involved the reaction of H-Idc-OH(cas: 79815-20-6).Safety of H-Idc-OH
The Article related to hydroxy ester asym synthesis, asym reformatsky reaction bromo ester ketone nickel indolinylmethanol catalyst, General Organic Chemistry: Synthetic Methods and other aspects.Safety of H-Idc-OH
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Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles