On December 16, 2015, Liu, Zhaotie; Liu, Huan; Wang, Chao; Chen, Jiangang; Liu, Zhongwen; Xiao, Jianliang published a patent.Synthetic Route of 52537-00-5 The title of the patent was A recyclable supported cyclic metal iridium catalyst and its preparation method and application in dehydrogenation reaction of indoline series compound. And the patent contained the following:
The present invention discloses a recyclable supported cyclic metal iridium catalyst and its preparation method and application in dehydrogenation reaction of indoline series compound The catalyst is pyrene-labeled cyclic metal iridium complex, which uses multi-walled carbon nanotubes as carrier. The pyrene-labeled cyclic metal iridium complex has structural formula as in Claim 1. The cyclic metal iridium complex uses iridium atom as coordination center, uses 4-methoxy-N-[1-(4- hydroxyphenyl)methylene]-aniline and pentamethyl cyclopentadiene as ligand. The preparation method includes: synthesis of 4-methoxy-N-(1-(4-hydroxyphenyl)methylene)-aniline; (2) synthesis of cyclic metal iridium complex; (3) synthesis of pyrene-labeled cyclic metal iridium complex; (5) preparation of the supported cyclic metal iridium catalyst. The inventive catalyst has simple preparation method, short preparation period, can achieve dehydrogenation reaction of indoline series compound in green solvent (mixed solvent of water and trifluoroethanol); the reaction conditions are mild, safe, green and efficient. The inventive catalyst can be recycled through simple centrifuge separation, and can keep its excellent catalytic performance after reused many times. The experimental process involved the reaction of 6-Chloro-2,3-dihydro-1H-indole(cas: 52537-00-5).Synthetic Route of 52537-00-5
The Article related to recyclable supported cyclic metal iridium catalyst dehydrogenation indoline, Catalysis, Reaction Kinetics, and Inorganic Reaction Mechanisms: Catalysts and other aspects.Synthetic Route of 52537-00-5
Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles