Merkt, Franziska K. et al. published their research in Chemistry – A European Journal in 2021 | CAS: 2521-13-3

5-Methoxy-1-methyl-1H-indole (cas: 2521-13-3) belongs to indole derivatives. Indole exists overwhelmingly in the 1H-indole form as do other simple indoles.Indole was synthesized in moderate yield via an o-naphthoquinone catalyzed tandem cross-coupling of substituted aniline and benzylamine under aerobic oxidation conditions.Related Products of 2521-13-3

Fluorescent Indolo[3,2-a]phenazines against Toxoplasma gondii: Concise Synthesis by Gold-Catalyzed Cycloisomerization with 1,2-Silyl Migration and ipso-Iodination Suzuki Sequence was written by Merkt, Franziska K.;Mazzone, Flaminia;Sazzadeh, Shabnam Shaneh;Bonda, Lorand;Hinz, Larissa K. E.;Gruber, Irina;Buchholz, Karin;Janiak, Christoph;Pfeffer, Klaus;Mueller, Thomas J. J.. And the article was included in Chemistry – A European Journal in 2021.Related Products of 2521-13-3 This article mentions the following:

A gold-catalyzed cycloisomerization of 2-indolyl-3-[(trimethylsilyl)ethynyl)]quinoxalines with concomitant 1,2-silyl shift forms 6-(trimethylsilyl)indolo[3,2-a]phenazines in moderate to excellent yield. These silylated heterocycles are readily transformed into 6-aryl-indolo[3,2-a]phenazines in moderate to good yield by one-pot ipso-iodination Suzuki coupling. The title compounds represent a novel type of tunable luminophore. Structure-property relationships for 6-aryl-indolo[3,2-a]phenazines obtained from Hammett correlations with σp+ substituent parameters indicate that emission maxima, Stokes shifts, and fluorescence quantum yields can be fine-tuned by the remote para-aryl substituent. Furthermore, indolo[3,2-a]phenazines were found to exhibit interesting activities against medically relevant pathogens such as the Apicomplexa parasite Toxoplasma gondii with an IC50 of up to 0.67±0.13μM. Thus, these compounds are promising candidates for novel anti-parasitic therapies. In the experiment, the researchers used many compounds, for example, 5-Methoxy-1-methyl-1H-indole (cas: 2521-13-3Related Products of 2521-13-3).

5-Methoxy-1-methyl-1H-indole (cas: 2521-13-3) belongs to indole derivatives. Indole exists overwhelmingly in the 1H-indole form as do other simple indoles.Indole was synthesized in moderate yield via an o-naphthoquinone catalyzed tandem cross-coupling of substituted aniline and benzylamine under aerobic oxidation conditions.Related Products of 2521-13-3

Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles