Malonodiamidines. III. Synthesis and condensation reactions of 1,2,3,4,6,7-hexahydro-7-imino-1,4-dimethyl-5H-1,4-diazepin-5-one was written by Meyer, Horst. And the article was included in Liebigs Annalen der Chemie in 1981.SDS of cas: 15540-90-6 The following contents are mentioned in the article:
[EtOC(:NH)]2CH2 reacted with MeNHCH2CH2NH2 to give 2,2′-methylenebis(imidazoline), whereas with MeNHCH2CH2NHMe the diazepines I (X = NH, O) were obtained, depending on the amount of H2O in the reaction. I (X = O) underwent cyclocondensations with mono- and diketones to give II (RR1 = N:CMeCH:CMe, NHCR2:CR3CHR4; R2 = Ph, C6H4NO2-3; R3 = CO2Et, H; R4 = Me, Ph) and III (R5 = H, 8-Me, 8-Br, R6 = H; R5 = 8-Me, 9-Cl, 7-Cl, R6 = Me). This study involved multiple reactions and reactants, such as 4,7-Dimethylindoline-2,3-dione (cas: 15540-90-6SDS of cas: 15540-90-6).
4,7-Dimethylindoline-2,3-dione (cas: 15540-90-6) belongs to indole derivatives. Indole is an important structural motif of various drugs, therapeutic leads besides its prevalence in numerous natural products, agrochemicals, perfumery, and dyes. Indole plays a fundamental role for QS in E. coli, being one of the signal molecules responsible for the transcription of a variety of genes (gabT, and tnaB ASTD). SDS of cas: 15540-90-6
Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles