Inducer-specific regulators of tumor necrosis factor alpha production was written by Miyachi, Hiroyuki;Azuma, Akihiko;Hioki, Erika;Kobayashi, Yoshiro;Iwaski, Shiego;Hashimoto, Yuichi. And the article was included in Chemical & Pharmaceutical Bulletin in 1996.SDS of cas: 5388-42-1 This article mentions the following:
Novel potent regulators of tumor necrosis factor alpha (TNF-α) production by a human promyelocytic leukemia cell one, HL-60, were prepared All the compounds showed inducer-specific and bidirectional regulation of TNF-α production, i.e., they enhanced 12-O-tetradecanoylphorbol-13-acetate-induced TNF-α production, while they inhibited okadaic acid-induced one. In the experiment, the researchers used many compounds, for example, 2-Phenylisoindolin-1-one (cas: 5388-42-1SDS of cas: 5388-42-1).
2-Phenylisoindolin-1-one (cas: 5388-42-1) belongs to indole derivatives. In addition to tryptophan, indigo, and indoleacetic acid, numerous compounds obtainable from plant or animal sources contain the indole molecular structure. They are capable of binding to a variety of receptors with high affinity and thus have applications in a wide range of therapeutic areas.SDS of cas: 5388-42-1
Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles