An article Efficient atom-economic one-pot multicomponent synthesis of benzylpyrazolyl coumarins and novel pyrano[2,3-c]pyrazoles catalysed by 2-aminoethanesulfonic acid (taurine) as a bio-organic catalyst WOS:000471365900001 published article about ANTITUMOR-ACTIVITY; ORGANIC-SYNTHESIS; GREEN SYNTHESIS; DERIVATIVES; ANTIOXIDANT; 4-HYDROXYCOUMARIN; CHEMISTRY; CANCER in [Chate, Asha V.; Shaikh, Badrodin Ayyub; Bondle, Giribala M.] Dr Babasaheb Ambedkar Marathwada Univ, Dept Chem, Aurangabad 431004, Maharashtra, India; [Sangle, Sunil M.] Rajaram Coll, Kolhapur, Maharashtra, India in 2019.0, Cited 71.0. The Name is 3-Hydroxybenzaldehyde. Through research, I have a further understanding and discovery of 100-83-4. Product Details of 100-83-4
The present work describes eco-friendly multicomponent protocol for the synthesis in excellent yields of structurally diverse benzylpyrazolyl coumarin 5 (a-s) involving the reaction of 4-hydroxycoumarin, ethyl acetoacetate, hydrazine hydrate/phenyl hydrazine hydrate and aldehydes, also novel pyrano[2,3-c]pyrazole derivatives 8 (a-k) integrated by isonicotinic acid hydrazide from reaction of aldehyde, ethyl acetoacetate, malononitrile with isoniazid, employing water as a reaction medium and 2-aminoethanesulfonic acid (taurine) as the catalyst. This new methodology endowed the advantages such as short reaction time, recovery of catalysts after catalytic reaction and reusing them without losing their activity and alleviate of operation. [GRAPHICS] .
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Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles