Safety of 4-Methoxybenzaldehyde. Authors Thi, TAD; Le-Nhat-Thuy, G; Thi, QGN; Thi, PH; Tuan, AN; Mai, HH; Ha, TN; Le, TA; Nguyen, TV in SPRINGER published article about in [Thi, Tuyet Anh Dang; Le-Nhat-Thuy, Giang; Thi, Quynh Giang Nguyen; Thi, Phuong Hoang; Tuan, Anh Nguyen; Mai, Ha Hoang; Ha, Thanh Nguyen; Van Nguyen, Tuyen] Vietnam Acad Sci & Technol, Inst Chem, 18 Hoang Quoc Viet St, Hanoi 100000, Vietnam; [Thi, Tuyet Anh Dang; Le-Nhat-Thuy, Giang; Thi, Quynh Giang Nguyen; Mai, Ha Hoang; Van Nguyen, Tuyen] Vietnam Acad Sci & Technol, Grad Univ Sci & Technol, 18 Hoang Quoc Viet St, Hanoi 100000, Vietnam; [Le, Tuan Anh] Vietnam Natl Univ Hanoi, Univ Sci, Fac Chem, 334 Nguyen Trai, Hanoi 100000, Vietnam in 2021.0, Cited 37.0. The Name is 4-Methoxybenzaldehyde. Through research, I have a further understanding and discovery of 123-11-5
Synthesis of novel 3-arylated 2-hydroxy-1,4-naphthoquinone derivatives via microwave-assisted three-component reaction starting from 2-hydroxy-1,4-naphthoquinone, tetronic acid, and various aromatic aldehydes has been described. This multicomponent domino reaction proceeded through the Knoevenagel condensation, Michael addition, deprotonation, and 1,3-H shift steps. Five of the synthesized compounds displayed good cytotoxic activity against two human cancer cell lines, KB and HepG2, with half maximal inhibitory concentration values in a range of 4-20 mu M.
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Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles