In homogeneous catalysis, the catalyst is in the same phase as the reactant. The number of collisions between reactants and catalyst is at a maximum.In a patent, 827-01-0, name is 5-Chloroindole-3-carboxaldehyde, introducing its new discovery. Application In Synthesis of 5-Chloroindole-3-carboxaldehyde
Antioxidant, cytotoxic activities, and structure-activity relationship of gallic acid-based indole derivatives
A new series of gallic hydrazones containing an indole moiety was synthesized through the reaction of gallic hydrazide and different indole carboxaldehydes. Their antioxidant activities were determined on DPPH radical scavenging and inhibition of lipid peroxidation. The in-vitro cytotoxic activities of the compounds were evaluated against HCT-116 (human colon cancer cell line) and MCF-7 (estrogen-dependent human breast cancer cell line) by the MTT method. An attempt to correlate the biological results with their structural characteristics has been done. A limited positive structure activity relationship was found between cytotoxic and antioxidant activities. Gallic acid derivatives are naturally occurring compounds with interesting biological properties. Similarly, indolic compounds represent an important class of therapeutical agents in medicinal chemistry. A series of hybrid molecules incorporating these two pharmacophores has been synthesized and assessed for their antioxidant and cytotoxic activities. Copyright
The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 827-01-0 is helpful to your research. Application In Synthesis of 5-Chloroindole-3-carboxaldehyde
Reference£º
Indole alkaloid derivatives as building blocks of natural products from?Bacillus thuringiensis?and?Bacillus velezensis?and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles