99-93-4, Name is 4′-Hydroxyacetophenone, molecular formula is C8H8O2, belongs to indole-building-block compound, is a common compound. In a patnet, author is Ban, Kazuho, once mentioned the new application about 99-93-4, Computed Properties of C8H8O2.
Arylation of indoles using cyclohexanones dually-catalyzed by niobic acid and palladium-on-carbons
3-Arylindoles were easily constructed from indoles and cyclohexanone derivatives using a combination of catalytic niobic acid-on-carbon (Nb2O5/C) and palladium-on-carbon (Pd/C) under heating conditions without any oxidants. The Lewis acidic Nb2O5/C promoted the nucleophilic addition of indoles to the cyclohexanones, and the subsequent dehydration and Pd/C-catalyzed dehydrogenation produced the 3-arylindoles. The additive 2,3-dimethyl-1,3-butadiene worked as a hydrogen acceptor to facilitate the dehydrogenation step.
We’ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, 99-93-4. The above is the message from the blog manager. Computed Properties of C8H8O2.
Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles