Authors Pertschi, R; Weibel, JM; Pale, P; Blanc, A in AMER CHEMICAL SOC published article about GOLD; CYCLIZATION; COMPLEXES; ENTRY; RING in [Pertschi, Romain; Weibel, Jean-Marc; Pale, Patrick; Blanc, Aurelien] Univ Strasbourg, Lab Synth React Organ & Catalyse, Inst Chim, CNRS,UMR 7177, 4 Rue Blaise Pascal, F-67070 Strasbourg, France in 2019.0, Cited 39.0. Category: indole-building-block. The Name is Benzyl Alcohol. Through research, I have a further understanding and discovery of 100-51-6
The synthesis of benzosultams has been achieved through a gold(I)-catalyzed ammonium formation strategy. Starting from easily available N-(2-alkynyl)-phenylsulfonyl azetidine derivatives, a cyclization reaction generated a spiroammonium gold intermediate that was ring-opened by nucleophilic alcohol or indole. This new methodology is compatible with the large variation in the substrates and nucleophiles and allowed the formation of benzosultams in high yield (18-98, 20 examples). This strategy also allowed the preparation of benzosultam analogs via iododeauration and subsequent cross-coupling reactions.
Category: indole-building-block. About Benzyl Alcohol, If you have any questions, you can contact Pertschi, R; Weibel, JM; Pale, P; Blanc, A or concate me.
Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles